Knockdown of mineralocorticoid or angiotensin II type 1 receptor gene expression in the paraventricular nucleus prevents angiotensin II hypertension in rats

Circulating Ang II activates an aldosterone-mineralocorticoid receptor (MR) – angiotensin II (Ang II) – angiotensin type 1 receptor (AT(1)R) pathway in the hypothalamus. To obtain insights into the actual neuronal projections involved, adeno-associated virus carrying small interfering RNA against ei...

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Dades bibliogràfiques
Publicat a:J Physiol
Autors principals: Chen, Aidong, Huang, Bing S, Wang, Hong-Wei, Ahmad, Monir, Leenen, Frans H H
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
Matèries:
Neuroscience: Cellular/Molecular
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229346/
https://ncbi.nlm.nih.gov/pubmed/24973408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.275560
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