Metabolic engineering of Bacillus amyloliquefaciens for poly-gamma-glutamic acid (γ-PGA) overproduction

We constructed a metabolically engineered glutamate-independent Bacillus amyloliquefaciens strain with considerable γ-PGA production. It was carried out by double-deletion of the cwlO gene and epsA-O cluster, as well as insertion of the vgb gene in the bacteria chromosome. The final generated strain...

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Bibliographische Detailangaben
Veröffentlicht in:Microb Biotechnol
Hauptverfasser: Feng, Jun, Gu, Yanyan, Sun, Yang, Han, Lifang, Yang, Chao, Zhang, Wei, Cao, Mingfeng, Song, Cunjiang, Gao, Weixia, Wang, Shufang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229325/
https://ncbi.nlm.nih.gov/pubmed/24986065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1751-7915.12136
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