Chronic Glucocorticoid Exposure-Induced Epididymal Adiposity Is Associated with Mitochondrial Dysfunction in White Adipose Tissue of Male C57BL/6J Mice

Prolonged and excessive glucocorticoids (GC) exposure resulted from Cushing's syndrome or GC therapy develops central obesity. Moreover, mitochondria are crucial in adipose energy homeostasis. Thus, we tested the hypothesis that mitochondrial dysfunction may contribute to chronic GC exposure-in...

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Veröffentlicht in:PLoS One
Hauptverfasser: Yu, Jie, Yu, Bing, He, Jun, Zheng, Ping, Mao, Xiangbing, Han, Guoquan, Chen, Daiwen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229254/
https://ncbi.nlm.nih.gov/pubmed/25389775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112628
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