CYLD Negatively Regulates Nontypeable Haemophilus influenzae-Induced IL-8 Expression via Phosphatase MKP-1-Dependent Inhibition of ERK

Nontypeable Haemophilus influenzae (NTHi), a Gram-negative bacterium, is the primary cause of otitis media in children and the exacerbation of chronic obstructive pulmonary disease in adults. A hallmark of both diseases is an overactive inflammatory response, including the upregulation of chemokines...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Wenzhuo Y., Komatsu, Kensei, Huang, Yuxian, Wu, Jing, Zhang, Wenhong, Lee, Ji-Yun, Miyata, Masanori, Xu, Haidong, Li, Jian-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229244/
https://ncbi.nlm.nih.gov/pubmed/25389768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112516
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