Glimepiride Promotes Osteogenic Differentiation in Rat Osteoblasts via the PI3K/Akt/eNOS Pathway in a High Glucose Microenvironment

Our previous studies demonstrated that glimepiride enhanced the proliferation and differentiation of osteoblasts and led to activation of the PI3K/Akt pathway. Recent genetic evidence shows that endothelial nitric oxide synthase (eNOS) plays an important role in bone homeostasis. In this study, we f...

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Publicado en:PLoS One
Autores principales: Ma, Pan, Gu, Bin, Xiong, Wei, Tan, Baosheng, Geng, Wei, Li, Jun, Liu, Hongchen
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229122/
https://ncbi.nlm.nih.gov/pubmed/25391146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112243
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