Phenotypic characterization of virological failure following lopinavir/ritonavir monotherapy using full-length gag–protease genes

OBJECTIVES: Major protease mutations are rarely observed following first-line failure with PIs and interpretation of genotyping results in this context may be difficult. We performed extensive phenotyping of viruses from five patients failing lopinavir/ritonavir monotherapy in the MONARK study witho...

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Dettagli Bibliografici
Pubblicato in:J Antimicrob Chemother
Autori principali: Sutherland, Katherine A., Mbisa, Jean L., Ghosn, Jade, Chaix, Marie-Laure, Cohen-Codar, Isabelle, Hue, Stephane, Delfraissy, Jean-Francois, Delaugerre, Constance, Gupta, Ravindra K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228778/
https://ncbi.nlm.nih.gov/pubmed/25096075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku296
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