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G-quadruplexes in viruses: function and potential therapeutic applications

G-rich nucleic acids can form non-canonical G-quadruplex structures (G4s) in which four guanines fold in a planar arrangement through Hoogsteen hydrogen bonds. Although many biochemical and structural studies have focused on DNA sequences containing successive, adjacent guanines that spontaneously f...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Métifiot, Mathieu, Amrane, Samir, Litvak, Simon, Andreola, Marie-Line
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227801/
https://ncbi.nlm.nih.gov/pubmed/25332402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku999
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