hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling

The increased cap-independent translation of anti-apoptotic proteins is involved in the development of drug resistance in lung cancer but signalling events regulating this are poorly understood. Fibroblast growth factor 2 (FGF-2) signalling-induced S6 kinase 2 (S6K2) activation is necessary, but the...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Roy, Rajat, Durie, Danielle, Li, Hui, Liu, Bing-Qian, Skehel, John Mark, Mauri, Francesco, Cuorvo, Lucia Veronica, Barbareschi, Mattia, Guo, Lin, Holcik, Martin, Seckl, Michael J., Pardo, Olivier E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227786/
https://ncbi.nlm.nih.gov/pubmed/25324306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku953
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