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Quantification of pre-mRNA escape rate and synergy in splicing

Splicing reactions generally combine high speed with accuracy. However, some of the pre-mRNAs escape the nucleus with a retained intron. Intron retention can control gene expression and increase proteome diversity. We calculated the escape rate for the yeast PTC7 intron and pre-mRNA. This prediction...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Bonde, Marie Mi, Voegeli, Sylvia, Baudrimont, Antoine, Séraphin, Bertrand, Becskei, Attila
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227748/
https://ncbi.nlm.nih.gov/pubmed/25352554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1014
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