The Feasibility of the Interferon Gamma Release Assay and Predictors of Discordance with the Tuberculin Skin Test for the Diagnosis of Latent Tuberculosis Infection in a Remote Aboriginal Community

BACKGROUND: The tuberculin skin test (TST) is the standard test used to screen for latent TB infection (LTBI) in the northern Canadian territory of Nunavut. Interferon gamma release assays (IGRA) are T cell blood-based assays to diagnose LTBI. The Bacillus Calmette-Guerin (BCG) vaccine is part of th...

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Veröffentlicht in:PLoS One
Hauptverfasser: Alvarez, Gonzalo G., Van Dyk, Deborah D., Davies, Naomi, Aaron, Shawn D., Cameron, D. William, Desjardins, Marc, Mallick, Ranjeeta, Obed, Natan, Baikie, Maureen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227715/
https://ncbi.nlm.nih.gov/pubmed/25386908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111986
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