Inhibition of GADD34, the Stress-Inducible Regulatory Subunit of the Endoplasmic Reticulum Stress Response, Does Not Enhance Functional Recovery after Spinal Cord Injury

Activation of the endoplasmic reticulum stress response (ERSR) is a hallmark of various pathological diseases and/or traumatic injuries. Restoration of ER homeostasis can contribute to improvement in the functional outcome of these diseases. Using genetic and pharmacological inhibition of the PERK-C...

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發表在:PLoS One
Main Authors: Saraswat Ohri, Sujata, Mullins, Ashley, Hetman, Michal, Whittemore, Scott R.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227638/
https://ncbi.nlm.nih.gov/pubmed/25386686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109703
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