Inhibition of the Cathepsin D-Type Proteinase of Macrophages by Pepstatin, a Specific Pepsin Inhibitor, and Other Substances

The macrophage is the main cell participating in chronic inflammation. It contains an acid-acting, cathepsin D-type proteinase with the specificity of pepsin, which may release mediators of the inflammatory process. To find new pharmaceutical inhibitors of this proteinase, we tested a variety of che...

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Detaylı Bibliyografya
Asıl Yazarlar: McAdoo, Martha H., Dannenberg, Arthur M., Hayes, Cara J., James, Stephen P., Sanner, John H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1973
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC422739/
https://ncbi.nlm.nih.gov/pubmed/4586863
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