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Sample size requirements to estimate key design parameters from external pilot randomised controlled trials: a simulation study

BACKGROUND: External pilot or feasibility studies can be used to estimate key unknown parameters to inform the design of the definitive randomised controlled trial (RCT). However, there is little consensus on how large pilot studies need to be, and some suggest inflating estimates to adjust for the...

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Detaylı Bibliyografya
Yayımlandı:Trials
Asıl Yazarlar: Teare, M Dawn, Dimairo, Munyaradzi, Shephard, Neil, Hayman, Alex, Whitehead, Amy, Walters, Stephen J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227298/
https://ncbi.nlm.nih.gov/pubmed/24993581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-15-264
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