Association between the Hypomethylation of Osteopontin and Integrin β3 Promoters and Vascular Smooth Muscle Cell Phenotype Switching in Great Saphenous Varicose Veins

Lower extremity varicose veins are a common condition in vascular surgery and proliferation of vascular smooth muscle cells (VSMCs) in the intima is a significant pathological feature of varicosity. However, the pathogenesis of varicose veins is not fully understood. Osteopontin (OPN) could promote...

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Udgivet i:Int J Mol Sci
Main Authors: Jiang, Han, Lun, Yu, Wu, Xiaoyu, Xia, Qian, Zhang, Xiaoyu, Xin, Shijie, Zhang, Jian
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227244/
https://ncbi.nlm.nih.gov/pubmed/25329616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms151018747
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