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BRD4 regulates Nanog expression in mouse embryonic stem cells and preimplantation embryos

Bromodomain-containing protein 4 (BRD4) is an important epigenetic reader implicated in the pathogenesis of a number of different cancers and other diseases. Brd4-null mouse embryos die shortly after implantation and are compromised in their ability to maintain the inner cell mass, which gives rise...

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Podrobná bibliografie
Vydáno v:Cell Death Differ
Hlavní autoři: Liu, W, Stein, P, Cheng, X, Yang, W, Shao, N-Y, Morrisey, E E, Schultz, R M, You, J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227152/
https://ncbi.nlm.nih.gov/pubmed/25146928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.124
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