BRD4 regulates Nanog expression in mouse embryonic stem cells and preimplantation embryos

Bromodomain-containing protein 4 (BRD4) is an important epigenetic reader implicated in the pathogenesis of a number of different cancers and other diseases. Brd4-null mouse embryos die shortly after implantation and are compromised in their ability to maintain the inner cell mass, which gives rise...

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Bibliographic Details
Published in:Cell Death Differ
Main Authors: Liu, W, Stein, P, Cheng, X, Yang, W, Shao, N-Y, Morrisey, E E, Schultz, R M, You, J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227152/
https://ncbi.nlm.nih.gov/pubmed/25146928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.124
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