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Two helices plus a linker: a small model substrate for eukaryotic RNase P.

Using precursor tRNA molecules to study RNA-protein interactions, we have identified an RNA motif recognized by eukaryotic RNase P (EC 3.1.26.5). Analysis of circularly permuted precursors indicates that interruptions in the sugar-phosphate backbone are not tolerated in the acceptor stem, in the T s...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Carrara, G, Calandra, P, Fruscoloni, P, Tocchini-Valentini, G P
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1995
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42271/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7708695/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2627
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