Protective role of frizzled-related protein B on matrix metalloproteinase induction in mouse chondrocytes

INTRODUCTION: Our objective was to investigate whether a lack of frizzled-related protein B (FrzB), an extracellular antagonist of the Wnt signaling pathways, could enhance cartilage degradation by facilitating the expression, release and activation of matrix metalloproteinases (MMPs) by chondrocyte...

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Bibliographic Details
Published in:Arthritis Res Ther
Main Authors: Bougault, Carole, Priam, Sabrina, Houard, Xavier, Pigenet, Audrey, Sudre, Laure, Lories, Rik J, Jacques, Claire, Berenbaum, Francis
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226985/
https://ncbi.nlm.nih.gov/pubmed/24984954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4599
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