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γδ T Lymphocytes as a First Line of Immune Defense: Old and New Ways of Antigen Recognition and Implications for Cancer Immunotherapy

Among γδT cells, the Vδ1 subset, resident in epithelial tissues, is implied in the defense against viruses, fungi, and certain hematological malignancies, while the circulating Vδ2 subpopulation mainly respond to mycobacteria and solid tumors. Both subsets can be activated by stress-induced molecule...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Poggi, Alessandro, Zocchi, Maria Raffaella
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226920/
https://ncbi.nlm.nih.gov/pubmed/25426121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00575
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