Effects of Promethazine-Hydrochloride on Human Polymorphonuclear Leukocytes

Promethazine hydrochloride at a concentration of 0.033 mg/ml has pronounced effects on leukocyte metabolism and function. The drug inhibits the phagocytosis-induced increases in O(2) consumption and hexose monophosphate shunt activity. Associated with these effects is an inhibition of the iodination...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: DeChatelet, Lawrence R., Qualliotine-Mann, Diane, Caldwell, Ronald, McCall, Charles E., Gusdon, John P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1973
Schlagworte:
Pathogenic Mechanisms, Ecology, and Epidemiology
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC422692/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4713692/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.7.3.403-408.1973
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