Investigation of the caspase-dependent mitochondrial apoptotic pathway in mononuclear cells of patients with systemic lupus erythematosus

BACKGROUND: This study aimed to explore the role of apoptosis initiators, caspase-9, caspase-10, mitochondrial anti-viral signaling protein (MAVS), and interferon regulatory factor 7 (pIRF7), in patients with systemic lupus erythematosus (SLE). METHODS: Leukocyte apoptosis was determined by flow cyt...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Su, Yu-Jih, Cheng, Tien-Tsai, Chen, Chung-Jen, Chang, Wen-Neng, Tsai, Nai-Wen, Kung, Chia-Te, Wang, Hung-Chen, Lin, Wei-Che, Huang, Chih-Cheng, Chang, Ya-Ting, Su, Chih-Min, Chiang, Yi-Fang, Cheng, Ben-Chung, Lin, Yu-Jun, Lu, Cheng-Hsien
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226892/
https://ncbi.nlm.nih.gov/pubmed/25370148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0303-1
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