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PATHOPHYSIOLOGY AND TREATMENT OF TYPE 2 DIABETES: PERSPECTIVES ON THE PAST, PRESENT AND FUTURE

Normal regulation of glucose metabolism is determined by a feedback loop involving the islet β-cell and insulin-sensitive tissues in which tissue sensitivity to insulin determines the magnitude of the β-cell response. When insulin resistance is present, the β-cell maintains normal glucose tolerance...

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Detalhes bibliográficos
Publicado no:Lancet
Main Authors: Kahn, Steven E., Cooper, Mark E., Del Prato, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226760/
https://ncbi.nlm.nih.gov/pubmed/24315620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(13)62154-6
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