POU2F1 activity regulates HOXD10 and HOXD11 promoting a proliferative and invasive phenotype in Head and Neck cancer

HOX genes are master regulators of organ morphogenesis and cell differentiation during embryonic development, and continue to be expressed throughout post-natal life. To test the hypothesis that HOX genes are dysregulated in head and neck squamous cell carcinoma (HNSCC) we defined their expression p...

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發表在:Oncotarget
Main Authors: Sharpe, Daniel J., Orr, Katy S., Moran, Michael, White, Sharon J., McQuaid, Stephen, Lappin, Terence R., Thompson, Alexander, James, Jacqueline A.
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2014
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226723/
https://ncbi.nlm.nih.gov/pubmed/25301728
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