Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease

Cumulative exposure to estrogen (E) and progesterone (P) over the menstrual cycle significantly influences the risk of developing breast cancer. Despite the dogma that PR in the breast merely serves as a marker of an active estrogen receptor (ER), and as an inhibitor of the proliferative actions of...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Hilton, Heidi N., Doan, Tram B., Graham, J. Dinny, Oakes, Samantha R., Silvestri, Audrey, Santucci, Nicole, Kantimm, Silke, Huschtscha, Lily I., Ormandy, Christopher J., Funder, John W., Simpson, Evan R., Kuczek, Elizabeth S., Leedman, Peter J., Tilley, Wayne D., Fuller, Peter J., Muscat, George E. O., Clarke, Christine L.
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2014
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226711/
https://ncbi.nlm.nih.gov/pubmed/25261374
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