Inhibition of lung tumor growth by targeting EGFR/VEGFR-Akt/NF-κB pathways with novel theanine derivatives

The molecularly targeted agents, including anti-VEGF or anti-EGFR monoclonal antibody and some inhibitors of EGFR tyrosine kinase, are effective in the treatment of non-small-cell lung cancer (NSCLC) to a certain extent, but the benefit for a proportion of patients is still limited. Hence, it is nec...

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Publicado en:Oncotarget
Main Authors: Zhang, Guoying, Ye, Xinshan, Ji, Dexin, Zhang, Huarong, Sun, Fujia, Shang, Chunqing, Zhang, Ying, Wu, Erxi, Wang, Fengfei, Wu, Fei, Tian, Huihui, Liu, Xin, Chen, Linlin, Liu, Kun, Wang, Yishan, Liu, Hanchen, Zhang, Wenhua, Guan, Yukun, Wang, Qinwen, Zhao, Xiaohang, Wan, Xiaochun
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2014
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226702/
https://ncbi.nlm.nih.gov/pubmed/25138052
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