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Molecular Basis for the Anchoring of Proto-Oncoprotein Nup98 to the Cytoplasmic Face of the Nuclear Pore Complex

The cytoplasmic filament nucleoporins of the nuclear pore complex (NPC) are critically involved in nuclear export and remodeling of mRNA ribonucleoprotein particles and are associated with various human malignancies. Here, we report the crystal structure of the Nup98 C-terminal autoproteolytic domai...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Mol Biol
Egile Nagusiak: Stuwe, Tobias T., von Borzyskowski, Lennart Schada, Davenport, Andrew M., Hoelz, André
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226653/
https://ncbi.nlm.nih.gov/pubmed/22480613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.03.024
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