Suppression of allo-human leucocyte antigen (HLA) antibodies secreted by B memory cells in vitro: intravenous immunoglobulin (IVIg) versus a monoclonal anti-HLA-E IgG that mimics HLA-I reactivities of IVIg

B memory cells remain in circulation and secrete alloantibodies without antigen exposure > 20 years after alloimmunization postpartum or by transplantation. These long-lived B cells are resistant to cytostatic drugs. Therapeutically, intravenous immunoglobulin (IVIg) is administered to reduce all...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Exp Immunol
Hauptverfasser: Zhu, D, Ravindranath, M H, Terasaki, P I, Miyazaki, T, Pham, T, Jucaud, V
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2014
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226597/
https://ncbi.nlm.nih.gov/pubmed/24611451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12307
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