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A Biomimetic Collagen Derived Peptide Exhibits Anti-Angiogenic Activity in Triple Negative Breast Cancer

We investigated the application of a mimetic 20 amino acid peptide derived from type IV collagen for treatment of breast cancer. We showed that the peptide induced a decrease of proliferation, adhesion, and migration of endothelial and tumor cells in vitro. We also observed an inhibition of triple n...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Rosca, Elena V., Penet, Marie-France, Mori, Noriko, Koskimaki, Jacob E., Lee, Esak, Pandey, Niranjan B., Bhujwalla, Zaver M., Popel, Aleksander S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226498/
https://ncbi.nlm.nih.gov/pubmed/25384034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111901
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