Reverse interferon signature is characteristic of antigen-presenting cells in human and rat spondyloarthritis

OBJECTIVE: In rats transgenic for HLA-B27 (B27 rat), the development of a disorder mimicking spondyloarthritis (SpA) is tightly correlated with DCs dysfunction. To dissect the underlying mechanisms, we studied the transcriptome of ex vivo purified CD103(+)CD4(+) DCs. METHODS: Transcriptome analysis...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Fert, Ingrid, Cagnard, Nicolas, Glatigny, Simon, Letourneur, Franck, Jacques, Sébastien, Smith, Judith A., Colbert, Robert A., Taurog, Joel D., Chiocchia, Gilles, Araujo, Luiza M., Breban, Maxime
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226235/
https://ncbi.nlm.nih.gov/pubmed/24757137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38318
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