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Connection between Tumor Suppressor BRCA1 and PTEN in Damaged DNA Repair

Genomic instability finally induces cell death or apoptosis. The tumor suppressor, phosphatase and tensin homolog on chromosome 10 (PTEN), is a dual-specificity phosphatase, which has protein phosphatase activity and lipid phosphatase activity that antagonizes PI3K activity. Cells that lack PTEN hav...

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書目詳細資料
發表在:Front Oncol
Main Authors: Minami, Akari, Nakanishi, Atsuko, Ogura, Yasunori, Kitagishi, Yasuko, Matsuda, Satoru
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226230/
https://ncbi.nlm.nih.gov/pubmed/25426449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00318
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