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Connection between Tumor Suppressor BRCA1 and PTEN in Damaged DNA Repair
Genomic instability finally induces cell death or apoptosis. The tumor suppressor, phosphatase and tensin homolog on chromosome 10 (PTEN), is a dual-specificity phosphatase, which has protein phosphatase activity and lipid phosphatase activity that antagonizes PI3K activity. Cells that lack PTEN hav...
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| Udgivet i: | Front Oncol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4226230/ https://ncbi.nlm.nih.gov/pubmed/25426449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00318 |
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