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An intramolecular lock facilitates folding and stabilizes the tertiary structure of Streptococcus mutans adhesin P1

The cariogenic bacterium Streptococcus mutans uses adhesin P1 to adhere to tooth surfaces, extracellular matrix components, and other bacteria. A composite model of P1 based on partial crystal structures revealed an unusual complex architecture in which the protein forms an elongated hybrid alpha/po...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Heim, Kyle P., Crowley, Paula J., Long, Joanna R., Kailasan, Shweta, McKenna, Robert, Brady, L. Jeannine
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226092/
https://ncbi.nlm.nih.gov/pubmed/25331888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413018111
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