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An intramolecular lock facilitates folding and stabilizes the tertiary structure of Streptococcus mutans adhesin P1
The cariogenic bacterium Streptococcus mutans uses adhesin P1 to adhere to tooth surfaces, extracellular matrix components, and other bacteria. A composite model of P1 based on partial crystal structures revealed an unusual complex architecture in which the protein forms an elongated hybrid alpha/po...
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| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4226092/ https://ncbi.nlm.nih.gov/pubmed/25331888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413018111 |
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