Chemoselective tarantula toxins report voltage activation of wild-type ion channels in live cells

Electrically excitable cells, such as neurons, exhibit tremendous diversity in their firing patterns, a consequence of the complex collection of ion channels present in any specific cell. Although numerous methods are capable of measuring cellular electrical signals, understanding which types of ion...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Tilley, Drew C., Eum, Kenneth S., Fletcher-Taylor, Sebastian, Austin, Daniel C., Dupré, Christophe, Patrón, Lilian A., Garcia, Rita L., Lam, Kit, Yarov-Yarovoy, Vladimir, Cohen, Bruce E., Sack, Jon T.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226076/
https://ncbi.nlm.nih.gov/pubmed/25331865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406876111
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