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Chronic fluoxetine treatment reduces parvalbumin expression and perineuronal nets in gamma-aminobutyric acidergic interneurons of the frontal cortex in adult mice

BACKGROUND: The selective serotonin reuptake inhibitor fluoxetine (FLX) is widely used to treat depression and anxiety disorders, but cellular mechanisms underlying the antidepressant effect of FLX remain largely unknown. The generally accepted effect of chronic FLX treatment is increased adult neur...

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Publicat a:Mol Brain
Autors principals: Ohira, Koji, Takeuchi, Rika, Iwanaga, Tsuyoshi, Miyakawa, Tsuyoshi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225860/
https://ncbi.nlm.nih.gov/pubmed/24228616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-43
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