Chronic fluoxetine treatment reduces parvalbumin expression and perineuronal nets in gamma-aminobutyric acidergic interneurons of the frontal cortex in adult mice

BACKGROUND: The selective serotonin reuptake inhibitor fluoxetine (FLX) is widely used to treat depression and anxiety disorders, but cellular mechanisms underlying the antidepressant effect of FLX remain largely unknown. The generally accepted effect of chronic FLX treatment is increased adult neur...

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Vydáno v:Mol Brain
Hlavní autoři: Ohira, Koji, Takeuchi, Rika, Iwanaga, Tsuyoshi, Miyakawa, Tsuyoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225860/
https://ncbi.nlm.nih.gov/pubmed/24228616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-43
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