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Chronic fluoxetine treatment reduces parvalbumin expression and perineuronal nets in gamma-aminobutyric acidergic interneurons of the frontal cortex in adult mice

BACKGROUND: The selective serotonin reuptake inhibitor fluoxetine (FLX) is widely used to treat depression and anxiety disorders, but cellular mechanisms underlying the antidepressant effect of FLX remain largely unknown. The generally accepted effect of chronic FLX treatment is increased adult neur...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Ohira, Koji, Takeuchi, Rika, Iwanaga, Tsuyoshi, Miyakawa, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225860/
https://ncbi.nlm.nih.gov/pubmed/24228616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-43
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