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Structural Architecture of SNP Effects on Complex Traits

Despite the discovery of copy-number variation (CNV) across the genome nearly 10 years ago, current SNP-based analysis methodologies continue to collapse the homozygous (i.e., A/A), hemizygous (i.e., A/0), and duplicative (i.e., A/A/A) genotype states, treating the genotype variable as irreducible o...

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Bibliographic Details
Published in:Am J Hum Genet
Main Authors: Gamazon, Eric R., Cox, Nancy J., Davis, Lea K.
Format: Artigo
Language:Inglês
Published: Elsevier 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225594/
https://ncbi.nlm.nih.gov/pubmed/25307299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2014.09.009
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