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Identification of a type I Ca(2+)/Mg(2+)-dependent endonuclease induced in maize cells exposed to camptothecin

BACKGROUND: Camptothecin is a plant alkaloid that specifically binds topoisomerase I, inhibiting its activity and inducing double stranded breaks in DNA and activating the cell responses to DNA damage. RESULTS: Maize cultured cells were incubated in the presence of different concentrations of campto...

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Pubblicato in:BMC Plant Biol
Autori principali: Sánchez-Pons, Núria, Vicient, Carlos M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225560/
https://ncbi.nlm.nih.gov/pubmed/24256432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2229-13-186
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