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Ionic selectivity and thermal adaptations within the voltage-gated sodium channel family of alkaliphilic Bacillus

Entry and extrusion of cations are essential processes in living cells. In alkaliphilic prokaryotes, high external pH activates voltage-gated sodium channels (Na(v)), which allows Na(+) to enter and be used as substrate for cation/proton antiporters responsible for cytoplasmic pH homeostasis. Here,...

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Publicat a:eLife
Autors principals: DeCaen, Paul G, Takahashi, Yuka, Krulwich, Terry A, Ito, Masahiro, Clapham, David E
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225499/
https://ncbi.nlm.nih.gov/pubmed/25385530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04387
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