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Use of dolutegravir in two INI-experienced patients with multiclass resistance resulted in excellent virological and immunological responses

INTRODUCTION: Dolutegravir is a second generation integrase inhibitor with a proposed high genetic barrier to resistance. However, in clinical trials, decreased virological response was seen in a subset of patients with prior exposure to raltegravir and multiple integrase resistance mutations. METHO...

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Detalhes bibliográficos
Publicado no:J Int AIDS Soc
Main Authors: Marije Hofstra, Laura, Nijhuis, Monique, Mudrikova, Tania, Fun, Axel, Schipper, Pauline, Schneider, Margriet, Wensing, Annemarie
Formato: Artigo
Idioma:Inglês
Publicado em: International AIDS Society 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225339/
https://ncbi.nlm.nih.gov/pubmed/25397500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7448/IAS.17.4.19755
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