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The efficacy, pharmacokinetics, safety and cardiovascular risks of switching nevirapine to rilpivirine in HIV-1 patients: the RPV switch study

INTRODUCTION: Nevirapine (NVP) induces cytochrome P450 3A4 by which rilpivirine (RPV) is metabolized. Switching NVP to RPV could result in decreased RPV exposure with subsequent virological failure and dyslipidemia because NVP is regarded as the least dyslipidemic, non-nucleoside, reverse transcript...

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Detalhes bibliográficos
Publicado no:J Int AIDS Soc
Main Authors: Rokx, Casper, Blonk, Maren, Verbon, Annelies, Burger, David, JA Rijnders, Bart
Formato: Artigo
Idioma:Inglês
Publicado em: International AIDS Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225336/
https://ncbi.nlm.nih.gov/pubmed/25397533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7448/IAS.17.4.19789
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