Activation-induced necroptosis contributes to B-cell lymphopenia in active systemic lupus erythematosus

B-cell abnormality including excessive activation and lymphopenia is a central feature of systemic lupus erythematosus (SLE). Although activation threshold, auto-reaction and death of B cells can be affected by intrinsical and/or external signaling, the underlying mechanisms are unclear. Herein, we...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Fan, H, Liu, F, Dong, G, Ren, D, Xu, Y, Dou, J, Wang, T, Sun, L, Hou, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225223/
https://ncbi.nlm.nih.gov/pubmed/25210799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.375
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