A novel variant of DNA polymerase ζ, Rev3ΔC, highlights differential regulation of Pol32 as a subunit of polymerase δ versus ζ in Saccharomyces cerevisiae

Unrepaired DNA lesions often stall replicative DNA polymerases and are bypassed by translesion synthesis (TLS) to prevent replication fork collapse. Mechanisms of TLS are lesion- and species-specific, with a prominent role of specialized DNA polymerases with relaxed active sites. After nucleotide(s)...

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Vydáno v:DNA Repair (Amst)
Hlavní autoři: Siebler, Hollie M., Lada, Artem G., Baranovskiy, Andrey G., Tahirov, Tahir H., Pavlov, Youri I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225194/
https://ncbi.nlm.nih.gov/pubmed/24819597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.04.013
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