A 40-bp Insertion/Deletion Polymorphism of Murine Double Minute2 (MDM2) Increased the Risk of Breast Cancer in Zahedan, Southeast Iran

Background: MDM2 (Murine Double Minute2) is an oncoprotein that inhibits the P53 activity. Overexpression of MDM2 gene has been reported in several human tumors. In the present study, we aimed to evaluate the impact of 40-bp insertion/deletion (ins/del) polymorphism on the promoter of MDM2 and susce...

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Detalhes bibliográficos
Publicado no:Iran Biomed J
Main Authors: Hashemi, Mohammad, Omrani, Mohsen, Eskandari-Nasab, Ebrahim, Hasani, Seyed-Shahaboddin, Mashhadi, Mohammad Ali, Taheri, Mohsen
Formato: Artigo
Idioma:Inglês
Publicado em: Pasteur Institute of Iran 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225065/
https://ncbi.nlm.nih.gov/pubmed/25326024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6091/ibj.13332.2014
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