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CSF LPV concentrations and viral load in viral suppressed patients on LPV/r monotherapy given once daily

INTRODUCTION: Plasma trough concentrations of lopinavir (LPV) given as LPV/r 800/200 mg once daily (OD) are reduced in comparison with 400/100 mg twice daily (BID). While OD dosage of LPV/r is sufficient to achieve viral suppression in plasma, data about drug penetration and viral suppression in cen...

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Bibliografiske detaljer
Udgivet i:J Int AIDS Soc
Main Authors: Tiraboschi, Juan, Imaz, Arkaitz, Ferrer, Elena, Saumoy, Maria, Rozas, Nerea, Maso, Marga, Vila, Antonia, Niubo, Jordi, Podzamczer, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: International AIDS Society 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224921/
https://ncbi.nlm.nih.gov/pubmed/25394093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7448/IAS.17.4.19587
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