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Contributions of charge-density research to medicinal chemistry

This article reviews efforts in accurate experimental charge-density studies with relevance to medicinal chemistry. Initially, classical charge-density studies that measure electron density distribution via least-squares refinement of aspherical-atom population parameters are summarized. Next, inter...

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Bibliografiske detaljer
Udgivet i:IUCrJ
Main Authors: Dittrich, Birger, Matta, Chérif F.
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224464/
https://ncbi.nlm.nih.gov/pubmed/25485126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252514018867
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