Disrupting Mitochondrial–Nuclear Coevolution Affects OXPHOS Complex I Integrity and Impacts Human Health

The mutation rate of the mitochondrial DNA (mtDNA), which is higher by an order of magnitude as compared with the nuclear genome, enforces tight mitonuclear coevolution to maintain mitochondrial activities. Interruption of such coevolution plays a role in interpopulation hybrid breakdown, speciation...

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Detalhes bibliográficos
Publicado no:Genome Biol Evol
Main Authors: Gershoni, Moran, Levin, Liron, Ovadia, Ofer, Toiw, Yasmin, Shani, Naama, Dadon, Sara, Barzilai, Nir, Bergman, Aviv, Atzmon, Gil, Wainstein, Julio, Tsur, Anat, Nijtmans, Leo, Glaser, Benjamin, Mishmar, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224335/
https://ncbi.nlm.nih.gov/pubmed/25245408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evu208
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