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Prognostic Impact of Deficient DNA Mismatch Repair and Mutations in KRAS, and BRAF(V600E) in Patients with Lymph Node-Positive Colon Cancer

While tumor stage remains the key determinant of colorectal cancer (CRC) prognosis and treatment, there is considerable stage-independent variability in clinical outcome. Molecular markers hold promise for explaining variations in clinical behavior, and may identify patient subsets with differential...

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Détails bibliographiques
Publié dans:Curr Colorectal Cancer Rep
Auteurs principaux: Zaanan, Aziz, Bachet, Jean-Baptiste, André, Thierry, Sinicrope, Frank A.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224319/
https://ncbi.nlm.nih.gov/pubmed/25386108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11888-014-0237-2
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