The size of the primary tumor and age at initial diagnosis are independent predictors of the metastatic behavior and survival of patients with SDHB-related pheochromocytoma and paraganglioma: a retrospective cohort study

BACKGROUND: Succinate dehydrogenase subunit B (SDHB) mutations are associated with aggressive pheochromocytoma (PHEO)/paraganglioma (PGL) behavior, often resulting in metastatic disease and fatal outcomes. These tumors are often larger, extra-adrenal, and contain lower catecholamine concentrations t...

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Dettagli Bibliografici
Pubblicato in:BMC Cancer
Autori principali: Schovanek, Jan, Martucci, Victoria, Wesley, Robert, Fojo, Tito, del Rivero, Jaydira, Huynh, Thanh, Adams, Karen, Kebebew, Electron, Frysak, Zdenek, Stratakis, Constantine A, Pacak, Karel
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223758/
https://ncbi.nlm.nih.gov/pubmed/25048685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-523
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