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Mad linker phosphorylations control the intensity and range of the BMP-activity gradient in developing Drosophila tissues

The BMP ligand Dpp, operates as a long range morphogen to control many important functions during Drosophila development from tissue patterning to growth. The BMP signal is transduced intracellularly via C-terminal phosphorylation of the BMP transcription factor Mad, which forms an activity gradient...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Aleman, Abigail, Rios, Marlyn, Juarez, Matthew, Lee, Daniel, Chen, Annan, Eivers, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223678/
https://ncbi.nlm.nih.gov/pubmed/25377173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06927
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