Systematic permutation testing in GWAS pathway analyses: identification of genetic networks in dilated cardiomyopathy and ulcerative colitis

BACKGROUND: Genome wide association studies (GWAS) are applied to identify genetic loci, which are associated with complex traits and human diseases. Analogous to the evolution of gene expression analyses, pathway analyses have emerged as important tools to uncover functional networks of genome-wide...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Genomics
Main Authors: Backes, Christina, Rühle, Frank, Stoll, Monika, Haas, Jan, Frese, Karen, Franke, Andre, Lieb, Wolfgang, Wichmann, H-Erich, Weis, Tanja, Kloos, Wanda, Lenhof, Hans-Peter, Meese, Eckart, Katus, Hugo, Meder, Benjamin, Keller, Andreas
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223581/
https://ncbi.nlm.nih.gov/pubmed/25052024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-622
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