Down-regulation of Ras-related Protein Rab 5C-dependent Endocytosis and Glycolysis in Cisplatin-resistant Ovarian Cancer Cell Lines

Drug resistance poses a major challenge to ovarian cancer treatment. Understanding mechanisms of drug resistance is important for finding new therapeutic targets. In the present work, a cisplatin-resistant ovarian cancer cell line A2780-DR was established with a resistance index of 6.64. The cellula...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Jin, Lixu, Huo, Yi, Zheng, Zhiguo, Jiang, Xiaoyong, Deng, Haiyun, Chen, Yuling, Lian, Qingquan, Ge, Renshan, Deng, Haiteng
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2014
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223497/
https://ncbi.nlm.nih.gov/pubmed/25096996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.033217
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