Immunoglobulin G (IgG) Fab Glycosylation Analysis Using a New Mass Spectrometric High-throughput Profiling Method Reveals Pregnancy-associated Changes

The N-linked glycosylation of the constant fragment (Fc) of immunoglobulin G has been shown to change during pathological and physiological events and to strongly influence antibody inflammatory properties. In contrast, little is known about Fab-linked N-glycosylation, carried by ∼20% of IgG. Here w...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Bondt, Albert, Rombouts, Yoann, Selman, Maurice H. J., Hensbergen, Paul J., Reiding, Karli R., Hazes, Johanna M. W., Dolhain, Radboud J. E. M., Wuhrer, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223489/
https://ncbi.nlm.nih.gov/pubmed/25004930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.039537
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