Integrative Structure–Function Mapping of the Nucleoporin Nup133 Suggests a Conserved Mechanism for Membrane Anchoring of the Nuclear Pore Complex

The nuclear pore complex (NPC) is the sole passageway for the transport of macromolecules across the nuclear envelope. Nup133, a major component in the essential Y-shaped Nup84 complex, is a large scaffold protein of the NPC's outer ring structure. Here, we describe an integrative modeling appr...

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Veröffentlicht in:Mol Cell Proteomics
Hauptverfasser: Kim, Seung Joong, Fernandez-Martinez, Javier, Sampathkumar, Parthasarathy, Martel, Anne, Matsui, Tsutomu, Tsuruta, Hiro, Weiss, Thomas M., Shi, Yi, Markina-Inarrairaegui, Ane, Bonanno, Jeffery B., Sauder, J. Michael, Burley, Stephen K., Chait, Brian T., Almo, Steven C., Rout, Michael P., Sali, Andrej
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2014
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Special Issue Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223481/
https://ncbi.nlm.nih.gov/pubmed/25139911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.040915
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